Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679578 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL9679571 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL20531111 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL14227034 | 0.94 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL29740118 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL18167329 | 0.91 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL28777391 | 0.91 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL15608320 | 0.91 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL7539326 | 0.91 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL7539324 | 0.91 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043330-A1 | Cystine Diamide Analogs For Cystinuria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043330-A1 | Cystine Diamide Analogs For Cystinuria | CTH, CBS, SLC7A11 | CYP1A2 4197/4885CYP2C9 3077/4885CYP2C19 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.