Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18842833 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL20940017 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18559596 | 1.00 | L3MBTL1 (0.50) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18848784 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL14028947 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18473557 | 0.98 | L3MBTL1 (0.51) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18910475 | 0.97 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL25067012 | 0.97 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL26751590 | 0.97 | L3MBTL1 (0.50) | L3MBTL1TDP1TBXAS1LMNACFTR | |
| Hydrochloric Acid SCHEMBL29251873 | 0.95 | L3MBTL1 (0.46) | L3MBTL1TDP1TBXAS1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045142-A1 | SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045142-A1 | SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES | MRPS23, RPP30, RPS19 | L3MBTL1 1159/4885TDP1 2524/4885TBXAS1 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.