Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003992 | 0.86 | DRD2 (0.59) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003629 | 0.84 | DRD2 (0.51) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003004 | 0.84 | DRD2 (0.56) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL30839786 | 0.83 | DRD2 (0.55) | KCNH2DRD2HTR7 | |
| SCHEMBL25003003 | 0.83 | DRD2 (0.55) | KCNH2DRD2HTR7 | |
| SCHEMBL25003854 | 0.83 | KCNH2 (0.53) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003035 | 0.82 | DRD2 (0.59) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003853 | 0.82 | DRD2 (0.59) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003011 | 0.81 | DRD2 (0.49) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25003990 | 0.79 | DRD2 (0.49) | KCNH2DRD2HTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |