Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003629 | 0.91 | DRD2 (0.51) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003004 | 0.88 | DRD2 (0.56) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003035 | 0.86 | DRD2 (0.59) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003853 | 0.86 | DRD2 (0.59) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003989 | 0.86 | KCNH2 (0.52) | DRD2DRD3HTR1AHTR2AKCNH2 | |
| SCHEMBL25003011 | 0.85 | DRD2 (0.49) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003990 | 0.82 | DRD2 (0.49) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003982 | 0.82 | DRD2 (0.58) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003041 | 0.82 | DRD2 (0.68) | DRD2MAPTDRD3HTR1AHTR2A | |
| SCHEMBL25003061 | 0.81 | DRD2 (0.58) | DRD2MAPTDRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011608-A1 | REGULATOR CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海枢境生物科技有限公司 | 2023-02-09 | — | — | WO | disclosed |