Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993210 | 0.85 | CYP2D6 (0.59) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL25004297 | 0.83 | MAOA (0.42) | RORCCYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL18334113 | 0.76 | CYP2D6 (0.47) | RORCCYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL10057646 | 0.75 | OPRM1 (0.63) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13904145 | 0.75 | CYP2D6 (0.46) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18334114 | 0.74 | CYP2D6 (0.68) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12167362 | 0.73 | CYP2D6 (0.45) | RORCCYP2D6OPRM1OPRD1OPRK1 | |
| SCHEMBL15715779 | 0.73 | OPRM1 (0.48) | OPRM1MAOBMAOASLC6A4SLC6A3 | |
| SCHEMBL10057658 | 0.72 | OPRM1 (0.51) | RORCCYP2D6OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL7406286 | 0.70 | CYP2D6 (0.41) | RORCCYP2D6OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | RORC 1172/4885CYP2D6 1872/4885OPRM1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.