Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31274754 | 0.84 | HPGD (0.39) | HPGDSMN1; SMN2LMNAAOC3TSHR | |
| SCHEMBL19346801 | 0.84 | HPGD (0.39) | HPGDSMN1; SMN2LMNAAOC3TSHR | |
| SCHEMBL31638058 | 0.79 | LOX (0.41) | SMN1; SMN2LMNAAOC3TSHRSLC6A4 | |
| SCHEMBL18348256 | 0.79 | NQO2 (0.37) | S1PR1MAPTL3MBTL1DHFR | |
| SCHEMBL22978591 | 0.78 | SMN1; SMN2 (0.38) | HPGDSMN1; SMN2LMNAAOC3TSHR | |
| SCHEMBL28392792 | 0.78 | ALDH1A1 (0.42) | HPGDSMN1; SMN2LMNAAOC3TSHR | |
| SCHEMBL26646826 | 0.78 | HSD17B10 (0.48) | HPGDSMN1; SMN2LMNAAOC3TSHR | |
| SCHEMBL31638306 | 0.78 | LOX (0.36) | SMN1; SMN2LMNAAOC3TSHRTDP1 | |
| SCHEMBL13765676 | 0.78 | GABRP (0.40) | HPGDSMN1; SMN2AOC3TSHRHSD17B10 | |
| SCHEMBL19466204 | 0.76 | ESR1 (0.38) | HPGDAOC3TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | HPGD 835/4885SMN1; SMN2 3774/4885LMNA 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.