Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26963218 | 0.77 | PTGS1 (0.39) | RXFP1PTGS1PTGS2KDM4EALOX15 | |
| SCHEMBL7489316 | 0.77 | RXFP1 (0.42) | RXFP1PTGS1PTGS2KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL31555571 | 0.75 | RXFP1 (0.41) | RXFP1PTGS1PTGS2KDM4EALOX15 | |
| SCHEMBL13733079 | 0.72 | RXFP1 (0.39) | RXFP1PTGS1PTGS2KDM4EALOX15 | |
| SCHEMBL21314950 | 0.69 | NOTUM (0.50) | PTGS1PTGS2KDM4EALOX15TSHR | |
| SCHEMBL14239269 | 0.69 | CHRM4 (0.36) | RXFP1PTGS1PTGS2KDM4EALOX15 | |
| SCHEMBL13732305 | 0.67 | PKM (0.36) | RXFP1PTGS1PTGS2KDM4EL3MBTL1 | |
| SCHEMBL13736015 | 0.67 | PKM (0.36) | RXFP1PTGS1PTGS2KDM4EL3MBTL1 | |
| SCHEMBL13735175 | 0.67 | RXFP1 (0.36) | RXFP1PTGS1PTGS2KDM4EL3MBTL1 | |
| SCHEMBL4734703 | 0.67 | BRD4 (0.38) | RXFP1PTGS1PTGS2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | RXFP1 2649/4885PTGS1 1287/4885PTGS2 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.