Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167787 | 0.80 | CHRM4 (0.53) | CHRM4KDM4EALDH1A1 | |
| SCHEMBL29205287 | 0.79 | TUBB4A (0.38) | KDM4EALDH1A1HPGDHSD17B10GRIN2D | |
| SCHEMBL14239265 | 0.72 | KDM4E (0.51) | CHRM4KDM4E | |
| SCHEMBL21314950 | 0.70 | NOTUM (0.50) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL25004848 | 0.69 | RXFP1 (0.41) | KDM4EALDH1A1HPGDALOX15HSD17B10 | |
| Methylamine SCHEMBL3235636 | 0.69 | P4HTM (0.55) | KDM4EALDH1A1ALOX15NAPRTHCAR2 | |
| SCHEMBL31359466 | 0.69 | P4HTM (0.59) | KDM4EALDH1A1ALOX15GABRA2GABRB2 | |
| SCHEMBL249720 | 0.69 | P4HTM (0.59) | KDM4EALDH1A1ALOX15GABRA2GABRB2 | |
| SCHEMBL21713058 | 0.68 | CYP2E1 (0.47) | ALDH1A1GABRA2GABRB2PTGS2HCAR2 | |
| SCHEMBL3745779 | 0.67 | CYP3A4 (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168315-A1 | SUBSTITUTED PIPERIDINES AS GPR119 MODULATORS FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-13 | — | — | WO | disclosed |