Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995358 | 0.81 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL25005993 | 0.80 | ACACB (0.34) | EPHX2SCN4ACYP2D6GPR183KCNH2 | |
| SCHEMBL25005865 | 0.74 | SNCA (0.32) | EPHX2SCN4ACYP2D6GPR183KCNH2 | |
| SCHEMBL23994238 | 0.74 | SNCA (0.32) | EPHX2SCN4ACYP2D6GPR183KCNH2 | |
| SCHEMBL25004989 | 0.74 | HTR2C (0.40) | HTR2CHTR2AHTR2BSLC6A4SLC6A2 | |
| SCHEMBL25113786 | 0.72 | RAB9A (0.59) | EPHX2SCN4AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL23995385 | 0.71 | SLC6A4 (0.43) | HTR2CHTR2AHTR2BSLC6A4SLC6A2 | |
| SCHEMBL17547128 | 0.70 | RAB9A (0.56) | EPHX2SCN4ADYRK1ANPC1RAB9A | |
| SCHEMBL30971432 | 0.69 | RAB9A (0.41) | EPHX2SCN4AGPR183KCNH2SLC6A2 | |
| SCHEMBL23995528 | 0.68 | HTR2C (0.47) | HTR2CHTR2AHTR2BSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | HTR2C 1699/4885HTR2A 1593/4885HTR2B 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.