Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006433 | 0.75 | NQO2 (0.38) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 | |
| SCHEMBL9408920 | 0.72 | PDE4B (0.49) | HDAC3HDAC1HDAC2CA1CA2 | |
| SCHEMBL8523377 | 0.70 | THRB (0.49) | HDAC3HDAC1HDAC2CA1CA2 | |
| Hydrochloric Acid SCHEMBL30725888 | 0.70 | HTT (0.56) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 | |
| SCHEMBL9440242 | 0.70 | HTT (0.52) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 | |
| SCHEMBL27457534 | 0.70 | HTT (0.52) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 | |
| SCHEMBL27314198 | 0.69 | TAS1R3 (0.47) | TAS1R3TAS1R1HDAC3HDAC1HDAC2 | |
| SCHEMBL3250292 | 0.69 | CA1 (0.53) | HDAC3HDAC1HDAC2CA1CA2 | |
| SCHEMBL3250283 | 0.69 | CA1 (0.53) | HDAC3HDAC1HDAC2CA1CA2 | |
| SCHEMBL28556177 | 0.68 | CA1 (0.49) | CA1CA2MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |