Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 8/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113873 | 0.84 | CYP1A2 (0.46) | PTPN1CYP3A4 | |
| SCHEMBL25008119 | 0.79 | SLC6A2 (0.41) | KIF11CYP3A4 | |
| SCHEMBL28846037 | 0.77 | PTPN5 (0.53) | PTPN5PTPN1RXRARXRBKIF11 | |
| SCHEMBL30913970 | 0.77 | PTPN1 (0.56) | PTPN5PTPN1RXRARXRBKIF11 | |
| SCHEMBL30914070 | 0.74 | ACSS2 (0.51) | PTPN5PTPN1RXRARXRB | |
| SCHEMBL1171983 | 0.74 | ACSS2 (0.51) | PTPN5PTPN1RXRARXRB | |
| SCHEMBL25007307 | 0.73 | PTPN5 (0.48) | PTPN5PTPN1RXRARXRBKIF11 | |
| SCHEMBL30222787 | 0.73 | PTPN5 (0.48) | PTPN5PTPN1RXRARXRBKIF11 | |
| Urea SCHEMBL16246927 | 0.73 | KIF11 (0.67) | PTPN5PTPN1KIF11CNR2SLC1A3 | |
| SCHEMBL27560417 | 0.73 | PTPN1 (0.59) | PTPN5PTPN1KIF11CNR2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380920-A1 | INHIBITORS FOR CORONAVIRUSES | Cocrystal Pharma, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-118103351-A | Coronavirus inhibitors | 共晶制药公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023014758-A1 | INHIBITORS FOR CORONAVIRUSES | COCRYSTAL PHARMA, INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| WO-2023014758-A1 | INHIBITORS FOR CORONAVIRUSES | COCRYSTAL PHARMA, INC. (US) | 2023-02-09 | — | — | WO | disclosed |