Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088076 | 0.84 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL5932513 | 0.83 | TSHR (0.46) | TSHRALDH1A1 | |
| SCHEMBL25005536 | 0.82 | TSHR (0.42) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL21158696 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL18388567 | 0.78 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL21754098 | 0.78 | TSHR (0.43) | TSHR | |
| SCHEMBL20629301 | 0.78 | TSHR (0.43) | TSHR | |
| SCHEMBL17919014 | 0.78 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL7100023 | 0.78 | TSHR (0.43) | TSHR | |
| SCHEMBL8125049 | 0.78 | TSHR (0.42) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038512-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230038512-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | TSHR 2599/4885ALDH1A1 4145/4885CYP3A4 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.