SCHEMBL25007628

SCHEMBL25007628

Nc1nc2c(ccc3sc4ccccc4c32)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
LMNA P02545 2/20 0.50
PDPK1 O15530 1/20 0.50
PDE10A Q9Y233 1/20 0.50
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 2/20 0.46
GPR3 P46089 1/20 0.43
MAPT P10636 4/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
LIMK1 P53667 2/20 0.39
CDK5 Q00535 1/20 0.39
CDK5R1 Q15078 1/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
DUSP3 P51452 1/20 0.39
BLM P54132 1/20 0.39
PTPN5 P54829 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25006959 0.79 GPR3 (0.43) ALDH1A1SMN1; SMN2TDP1CYP3A4GPR3
SCHEMBL25006315 0.79 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2LMNAPDE10ATDP1
SCHEMBL1801464 0.78 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2LMNAPDPK1PDE10A
Bromide SCHEMBL4961408 0.77 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAPDPK1PDE10A
SCHEMBL1636538 0.74 GPR3 (0.68) ALDH1A1SMN1; SMN2TDP1CYP3A4GPR3
SCHEMBL6118333 0.74 SMN1; SMN2 (0.59) ALDH1A1SMN1; SMN2LMNAPDPK1PDE10A
SCHEMBL25007678 0.73 GPR3 (0.37) ALDH1A1SMN1; SMN2LMNATDP1CYP3A4
SCHEMBL17281511 0.73 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAPDPK1PDE10A
SCHEMBL8603051 0.72 HPRT1 (0.48) ALDH1A1SMN1; SMN2LMNAPDPK1PDE10A
SCHEMBL30899154 0.71 GPR3 (0.56) ALDH1A1SMN1; SMN2TDP1CYP3A4GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023012711-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-02-09 WO disclosed