Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007239 | 0.85 | GPR84 (0.42) | GPR84ALDH1A1 | |
| SCHEMBL25008380 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL25008413 | 0.75 | GPR84 (0.40) | GPR84 | |
| SCHEMBL25006844 | 0.74 | GPR84 (0.39) | GPR84 | |
| SCHEMBL8479304 | 0.70 | GPR84 (0.48) | GPR84 | |
| SCHEMBL25007782 | 0.70 | GPR84 (0.36) | GPR84 | |
| SCHEMBL25006614 | 0.70 | GPR84 (0.45) | GPR84ALDH1A1CYP2C19POLB | |
| SCHEMBL23415802 | 0.69 | GPR84 (0.44) | GPR84ALDH1A1HCAR2HCAR3 | |
| SCHEMBL23415846 | 0.69 | GPR84 (0.44) | GPR84ALDH1A1HCAR2HCAR3 | |
| SCHEMBL23415837 | 0.69 | GPR84 (0.44) | GPR84ALDH1A1HCAR2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |