SCHEMBL25008057

SCHEMBL25008057

C=C(CC)C[C@H](N)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
GRIK1 P39086 3/20 0.32
GRIK2 Q13002 2/20 0.32
GRIA4 P48058 1/20 0.32
GRIK3 Q13003 1/20 0.32
GRIK5 Q16478 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
KIF11 P52732 1/20 0.31
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25006833 0.79 ALDH1A1 (0.36) CA1CA2GRIK1GRIK2GRM1
SCHEMBL10458343 0.79 ALDH1A1 (0.36) CA1CA2GRIK1GRIK2GRM1
SCHEMBL21557288 0.79 TDP1 (0.38) CA1CA2GRIK1GRIA4GRIK3
Hydrochloric Acid SCHEMBL29414281 0.78 ALDH1A1 (0.36) CA1CA2GRIK1GRIK2GRM1
SCHEMBL15451505 0.78 ESRRB (0.36) CA1CA2SMN1; SMN2ZDHHC7KMT2A
SCHEMBL25660937 0.77 GRIK1 (0.56) GRIK1GRIK2GRIA4GRIK3GRIK5
SCHEMBL25660325 0.77 GRIK1 (0.56) GRIK1GRIK2GRIA4GRIK3GRIK5
SCHEMBL1427176 0.76 GRIK1 (0.41) GRIK1GRIK2GRM1GRM2SMN1; SMN2
SCHEMBL11292145 0.76 ALDH1A1 (0.33) CA1CA2SMN1; SMN2ZDHHC7KMT2A
SCHEMBL8894673 0.75 SMN1; SMN2 (0.42) CA1CA2SMN1; SMN2ZDHHC7KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398757-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. 2024-12-05 US disclosed
EP-4380920-A1 INHIBITORS FOR CORONAVIRUSES Cocrystal Pharma, Inc. (US) 2024-06-12 EP disclosed
CN-118103351-A Coronavirus inhibitors 共晶制药公司 2024-05-28 CN disclosed
WO-2023014758-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. (US) 2023-02-09 WO disclosed
WO-2023014758-A1 INHIBITORS FOR CORONAVIRUSES COCRYSTAL PHARMA, INC. (US) 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240398757-A1 INHIBITORS FOR CORONAVIRUSES ACE, ACE2, SARS1 CA1 1862/4885CA2 1835/4885GRIK1 4040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.