Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164454 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL4144659 | 0.83 | ALDH1A1 (0.36) | ALDH1A1CA1CA2SMN1; SMN2TSHR | |
| SCHEMBL684579 | 0.80 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2ZDHHC7TSHRMME | |
| SCHEMBL25457592 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CA1CA2SMN1; SMN2ZDHHC7 | |
| SCHEMBL15451505 | 0.78 | ESRRB (0.36) | ALDH1A1CA1CA2SMN1; SMN2ZDHHC7 | |
| SCHEMBL446634 | 0.77 | MGAM (0.42) | ALDH1A1CA1CA2SMN1; SMN2TSHR | |
| SCHEMBL9346762 | 0.77 | KMT2A (0.36) | ALDH1A1CA1CA2SMN1; SMN2TSHR | |
| SCHEMBL222338 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1CA1CA2SMN1; SMN2ZDHHC7 | |
| SCHEMBL25008057 | 0.76 | CA1 (0.33) | ALDH1A1CA1CA2SMN1; SMN2ZDHHC7 | |
| SCHEMBL12877143 | 0.76 | GAA (0.48) | ALDH1A1CA1CA2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064306-A1 | Substituted tetrahydrofuran herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-11-10 | — | — | EP | disclosed |