Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 4/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497592 | 0.85 | TSHR (0.45) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL14906969 | 0.83 | ALDH1A1 (0.56) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL2501033 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10HDAC1HDAC2 | |
| SCHEMBL4148009 | 0.82 | SMN1; SMN2 (0.46) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL29097678 | 0.82 | GRM2 (0.43) | DPP4FEN1ALOX5AP | |
| SCHEMBL17867987 | 0.78 | TSHR (0.46) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL31607699 | 0.78 | TSHR (0.68) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL2502464 | 0.78 | TSHR (0.56) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL30839748 | 0.78 | TSHR (0.68) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL30839743 | 0.78 | TSHR (0.68) | TSHRCYP3A4ALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030527-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | SMIDT SEBASTIAN PEER | 2010-10-07 | — | — | US | disclosed |
| US-7709684-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2029519-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | BASF SE (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2007138089-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | CBR3, HRH3, CBR1 | TSHR 20/4885CYP3A4 671/4885ALDH1A1 2554/4885 |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | CBR3, HRH3, CBR1 | TSHR 14/4885CYP3A4 666/4885ALDH1A1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.