Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | FEN1 | P39748 | 8/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503083 | 0.84 | ALDH1A1 (0.50) | ALDH1A1FEN1ALOX5APHDAC1HDAC2 | |
| SCHEMBL2500848 | 0.82 | TSHR (0.45) | ALDH1A1FEN1ALOX5APHDAC1HDAC2 | |
| SCHEMBL3793523 | 0.81 | TAAR1 (0.52) | ALDH1A1TAAR1GAAHTTPTGS1 | |
| SCHEMBL29462674 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HDAC1TAAR1GAAHTT | |
| SCHEMBL29647556 | 0.78 | FEN1 (0.55) | ALDH1A1FEN1ALOX5APPTGS1PTGS2 | |
| SCHEMBL30325664 | 0.78 | TAAR1 (0.59) | ALDH1A1TAAR1GAAHTTKDM4E | |
| SCHEMBL396633 | 0.78 | FEN1 (0.55) | ALDH1A1FEN1ALOX5APPTGS1PTGS2 | |
| SCHEMBL2493219 | 0.77 | AHR (0.50) | ALDH1A1KDM4EDHFRAKR1C3AKR1C2 | |
| SCHEMBL30927149 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HDAC1CYP1A1GAAHTT | |
| SCHEMBL28228449 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HDAC1CYP1A1TAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030527-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | SMIDT SEBASTIAN PEER | 2010-10-07 | — | — | US | disclosed |
| US-7709684-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2029519-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | BASF SE (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2007138089-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | CBR3, HRH3, CBR1 | ALDH1A1 2554/4885FEN1 3083/4885ALOX5AP 2946/4885 |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | CBR3, HRH3, CBR1 | ALDH1A1 1911/4885FEN1 3260/4885ALOX5AP 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.