Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25000952 | 1.00 | MCHR1 (0.42) | MCHR1DHFRDCPSCNR2GCK | |
| SCHEMBL29210919 | 1.00 | MCHR1 (0.42) | MCHR1DHFRDCPSCNR2GCK | |
| SCHEMBL25009912 | 0.85 | P2RX3 (0.32) | DHFRP2RX3 | |
| SCHEMBL25001114 | 0.83 | MCHR1 (0.37) | MCHR1DHFRDCPSCNR2GCK | |
| SCHEMBL25009352 | 0.83 | MCHR1 (0.37) | MCHR1DHFRDCPSCNR2GCK | |
| SCHEMBL25009709 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSCNR2GCK | |
| SCHEMBL25000951 | 0.80 | P2RX3 (0.40) | MCHR1P2RX3 | |
| SCHEMBL29223784 | 0.78 | PLAU (0.46) | — | |
| SCHEMBL22804656 | 0.76 | GCK (0.37) | GCKABL1 | |
| SCHEMBL22804653 | 0.76 | GCK (0.37) | GCKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |