Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 4/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009568 | 0.84 | MCHR1 (0.38) | MCHR1UHRF1DHFRDCPSABL1 | |
| SCHEMBL29210919 | 0.83 | MCHR1 (0.42) | MCHR1DHFRDCPSABL1CNR2 | |
| SCHEMBL25009529 | 0.83 | MCHR1 (0.42) | MCHR1DHFRDCPSABL1CNR2 | |
| SCHEMBL25000952 | 0.83 | MCHR1 (0.42) | MCHR1DHFRDCPSABL1CNR2 | |
| SCHEMBL25011567 | 0.75 | UHRF1 (0.48) | UHRF1DHFR | |
| SCHEMBL14353575 | 0.74 | UHRF1 (0.56) | UHRF1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18478403 | 0.70 | GCK (0.40) | MCHR1DHFRDCPSABL1CNR2 | |
| SCHEMBL25010693 | 0.70 | MCHR1 (0.43) | MCHR1DHFRDCPSABL1GRM5 | |
| SCHEMBL30271340 | 0.70 | MCHR1 (0.43) | MCHR1DHFRDCPSABL1GRM5 | |
| SCHEMBL25010689 | 0.70 | MCHR1 (0.43) | MCHR1DHFRDCPSABL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |