Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271340 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSALDH1A1SMN1; SMN2 | |
| SCHEMBL25010689 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSALDH1A1SMN1; SMN2 | |
| SCHEMBL25001112 | 0.83 | CYP1A2 (0.38) | MCHR1DHFRDCPSCDK1CDK2 | |
| SCHEMBL25010693 | 0.83 | MCHR1 (0.43) | MCHR1DHFRDCPSALDH1A1SMN1; SMN2 | |
| SCHEMBL21585395 | 0.77 | KMT2A (0.41) | SMN1; SMN2GRM5CDK1CDK2KDM4E | |
| SCHEMBL29210853 | 0.77 | CTSB (0.43) | MCHR1ALDH1A1SMN1; SMN2CDK1CDK2 | |
| SCHEMBL29210854 | 0.77 | CTSB (0.43) | MCHR1ALDH1A1SMN1; SMN2CDK1CDK2 | |
| SCHEMBL19121798 | 0.73 | MEN1 (0.49) | ALDH1A1SMN1; SMN2NPSR1CDK1CDK2 | |
| SCHEMBL21585390 | 0.72 | LPAR1 (0.36) | KMT2A | |
| SCHEMBL25742983 | 0.71 | CCR1 (0.31) | KDM4EUSP2HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |