Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501212 | 0.87 | MAPK1 (0.51) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL27735807 | 0.87 | MAPK1 (0.59) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL25561346 | 0.85 | MAPK1 (0.56) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL2502447 | 0.84 | TDP1 (0.49) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL11516745 | 0.84 | MAPK1 (0.69) | MAPK1TSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL9732213 | 0.81 | MAPK1 (0.66) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL24030376 | 0.78 | ALDH1A1 (0.53) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL2503092 | 0.78 | MAPK1 (0.49) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL19997893 | 0.77 | ALDH1A1 (0.61) | MAPK1TSHRTDP1HSD11B1ALDH1A1 | |
| SCHEMBL5415102 | 0.77 | PDE7A (0.58) | MAPK1TSHRTDP1HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030527-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | SMIDT SEBASTIAN PEER | 2010-10-07 | — | — | US | disclosed |
| US-7709684-B2 | Process for preparing substituted biphenyls | BASF SE (DE) | 2010-05-04 | — | — | US | disclosed |
| EP-2029519-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | BASF SE (DE) | 2009-01-01 | — | — | US | disclosed |
| WO-2007138089-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | BASF SE (DE) | 2007-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256418-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS | CBR3, HRH3, CBR1 | MAPK1 2122/4885TSHR 20/4885TDP1 1492/4885 |
| US-20090005597-A1 | Process for Preparing Substituted Biphenyls | CBR3, HRH3, CBR1 | MAPK1 1142/4885TSHR 14/4885TDP1 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.