Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732213 | 0.87 | MAPK1 (0.66) | MAPK1TSHRHSD11B1PDE7AL3MBTL1 | |
| SCHEMBL11516745 | 0.87 | MAPK1 (0.69) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL2501193 | 0.87 | MAPK1 (0.56) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL28775421 | 0.86 | MAPK1 (0.55) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL25561346 | 0.84 | MAPK1 (0.56) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL4583256 | 0.83 | ALDH1A1 (0.59) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL21145383 | 0.83 | GABRA1 (0.46) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL27735860 | 0.83 | TDP1 (0.51) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL19997893 | 0.83 | ALDH1A1 (0.61) | MAPK1TSHRHSD11B1MAPTHPGD | |
| SCHEMBL5415102 | 0.83 | PDE7A (0.58) | MAPK1TSHRHSD11B1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374799-B | Process for preparing substituted biphenyls | BASF SE | 2012-05-23 | — | — | CN | disclosed |
| CN-101374799-A | Process for preparing substituted biphenyls | BASF SE (DE) | 2009-02-25 | — | — | CN | disclosed |