Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250635 | 0.97 | P2RX4 (0.32) | P2RX4TDP1GPBAR1MAPK8MAPK9 | |
| SCHEMBL212092 | 0.94 | P2RX4 (0.33) | P2RX4MAP4K1 | |
| SCHEMBL210546 | 0.93 | CTSK (0.34) | P2RX4TDP1 | |
| SCHEMBL212269 | 0.91 | P2RX4 (0.33) | P2RX4MAP4K1 | |
| SCHEMBL209966 | 0.89 | CTSK (0.34) | P2RX4TDP1 | |
| SCHEMBL2726553 | 0.88 | MAP4K1 (0.31) | TDP1GPBAR1MAPK8MAPK9MAPK10 | |
| SCHEMBL213060 | 0.87 | CTSK (0.35) | P2RX4TDP1 | |
| SCHEMBL211056 | 0.86 | MAP4K1 (0.30) | P2RX4MAP4K1 | |
| SCHEMBL211133 | 0.86 | CTSK (0.35) | — | |
| SCHEMBL211083 | 0.86 | CTSK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |