Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30269882 | 1.00 | HTT (0.37) | HTTBTN3A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13469494 | 0.92 | HTT (0.39) | HTTBTN3A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30472855 | 0.92 | HTT (0.39) | HTTBTN3A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23044633 | 0.87 | MEN1 (0.39) | HTTBTN3A1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28986476 | 0.86 | BTN3A1 (0.41) | HTTBTN3A1ALDH1A1KDM4EOGG1 | |
| SCHEMBL29895522 | 0.86 | BTN3A1 (0.41) | HTTBTN3A1ALDH1A1KDM4EOGG1 | |
| SCHEMBL29637567 | 0.85 | BTN3A1 (0.38) | HTTBTN3A1ALDH1A1HSD17B10OGG1 | |
| SCHEMBL25013420 | 0.85 | BTN3A1 (0.44) | BTN3A1ALDH1A1KMT2AMEN1 | |
| SCHEMBL22065060 | 0.84 | BTN3A1 (0.42) | BTN3A1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL20833545 | 0.84 | BTN3A1 (0.42) | BTN3A1ALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230040586-A1 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | TYMP, PNP, DUT | HTT 3194/4885BTN3A1 3427/4885ALDH1A1 1269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.