SCHEMBL23044633

SCHEMBL23044633

COC(=O)[C@H](C)N[P@@](=O)(Oc1c(F)c(F)c(F)c(F)c1F)Oc1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ PGR P06401 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ BTN3A1 O00481 6/20 0.37
▸ KDM4E B2RXH2 2/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ OGG1 O15527 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ NR2E1 Q9Y466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28401524 0.91 BTN3A1 (0.41) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL20845948 0.91 BTN3A1 (0.41) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL29692333 0.91 BTN3A1 (0.41) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL30435963 0.91 BTN3A1 (0.41) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL29895522 0.90 BTN3A1 (0.41) ALDH1A1BTN3A1KDM4EOGG1HTT
SCHEMBL28986476 0.90 BTN3A1 (0.41) ALDH1A1BTN3A1KDM4EOGG1HTT
SCHEMBL21192831 0.90 ALDH1A1 (0.39) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL20840403 0.90 ALDH1A1 (0.39) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL23827926 0.90 ALDH1A1 (0.39) MEN1KMT2AALDH1A1PGRGAA
SCHEMBL28529771 0.90 ALDH1A1 (0.39) MEN1KMT2AALDH1A1PGRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637441-B2 Prodrugs of the tyrosine kinase inhibitor for treating cancer Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-05-26 — — US disclosed
EP-4021912-A1 PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2022-07-06 — — EP disclosed
US-20210078970-A1 PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
WO-2021035360-A1 PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210078970-A1 PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER ABL1, FLT3, SRC MEN1 1705/4885KMT2A 1351/4885ALDH1A1 866/4885
US-12637441-B2 Prodrugs of the tyrosine kinase inhibitor for treating cancer EGFR, ERBB2, MET MEN1 2789/4885KMT2A 1094/4885ALDH1A1 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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