Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250872 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCYP3A4MEN1 | |
| SCHEMBL27544700 | 0.74 | ALDH1A1 (0.46) | ALOX5ALDH1A1GLATSHRSMN1; SMN2 | |
| SCHEMBL256802 | 0.73 | ADRB2 (0.56) | ALOX5ALDH1A1SMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL352653 | 0.73 | ADRB2 (0.56) | ALOX5ALDH1A1SMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL116807 | 0.73 | ADRB2 (0.56) | ALOX5ALDH1A1SMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL5218475 | 0.73 | TP53 (0.43) | ALDH1A1GLATSHRSMN1; SMN2MLYCD | |
| SCHEMBL915703 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCYP1A2CYP3A4 | |
| SCHEMBL8342856 | 0.72 | ALDH1A1 (0.47) | ALDH1A1GLATSHRSMN1; SMN2MLYCD | |
| Bromide SCHEMBL25277530 | 0.71 | ADRB2 (0.54) | ALOX5ALDH1A1SMN1; SMN2CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL14977817 | 0.71 | ADRB2 (0.54) | ALOX5ALDH1A1SMN1; SMN2CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401275-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | Respiratorius AB (SE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097410-A1 | NOVEL BRONCHODILATING DIAZAHETEROARYLS | RESPIRATORIUS AB (SE) | 2010-09-02 | — | — | WO | disclosed |