Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25013290 | 0.95 | TTK (0.46) | TTKPTK6 | |
| SCHEMBL25013149 | 0.94 | TTK (0.46) | TTKPTK6 | |
| SCHEMBL25013682 | 0.91 | TTK (0.47) | TTKPTK6 | |
| SCHEMBL25013088 | 0.88 | TTK (0.51) | TTKPTK6 | |
| SCHEMBL25013144 | 0.83 | TTK (0.49) | TTKPTK6 | |
| SCHEMBL25013086 | 0.82 | PTK6 (0.54) | TTKPTK6 | |
| SCHEMBL25013102 | 0.81 | TTK (0.53) | TTKPTK6 | |
| SCHEMBL25013672 | 0.81 | TTK (0.55) | TTKPTK6 | |
| SCHEMBL25013701 | 0.80 | TTK (0.50) | TTKPTK6 | |
| SCHEMBL22123443 | 0.80 | TTK (0.48) | TTKPTK6BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |