Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.34 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24870892 | 0.87 | PTK6 (0.43) | PTK6KDM4EGAASMN1; SMN2EGFR | |
| SCHEMBL30171755 | 0.87 | PTK6 (0.43) | PTK6KDM4EGAASMN1; SMN2EGFR | |
| SCHEMBL30183416 | 0.85 | PTK6 (0.50) | PTK6KDM4EGAASMN1; SMN2EGFR | |
| SCHEMBL24112398 | 0.83 | PTK6 (0.44) | PTK6MAPTMCHR1TTKLCK | |
| SCHEMBL22124504 | 0.82 | PTK6 (0.42) | PTK6ALKMCHR1TTK | |
| SCHEMBL30171940 | 0.82 | PTK6 (0.51) | PTK6EGFRERBB2HTR4LCK | |
| SCHEMBL22122928 | 0.82 | PTK6 (0.51) | PTK6EGFRERBB2HTR4LCK | |
| SCHEMBL25450752 | 0.82 | PTK6 (0.41) | PTK6KDM4EGAASMN1; SMN2MCHR1 | |
| SCHEMBL22123532 | 0.81 | PTK6 (0.42) | PTK6EGFRERBB2ALKMCHR1 | |
| SCHEMBL22123658 | 0.81 | PTK6 (0.42) | PTK6EGFRERBB2ALKMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |