Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22894411 | 0.85 | GLA (0.39) | GLAMAPK1ALDH1A1MEN1TSHR | |
| SCHEMBL21984860 | 0.83 | NTRK1 (0.41) | GLAMAPK1GAAMEN1TSHR | |
| SCHEMBL25701589 | 0.81 | HDAC3 (0.44) | L3MBTL1 | |
| SCHEMBL15495576 | 0.81 | KDM4E (0.46) | GLAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL13986279 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1MEN1TSHRKMT2AL3MBTL1 | |
| SCHEMBL13167820 | 0.77 | SRC (0.39) | GLAMAPK1ALDH1A1MEN1TSHR | |
| SCHEMBL908481 | 0.77 | LMNA (0.43) | GLAALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL11910527 | 0.77 | SRC (0.41) | GLAMAPK1ALDH1A1MEN1TSHR | |
| SCHEMBL15495602 | 0.76 | KMT2A (0.45) | MAPK1ALDH1A1GAAMEN1TSHR | |
| SCHEMBL15495578 | 0.76 | KDM4E (0.41) | GLAMAPK1ALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011639-A1 | OLIGOSACCHARIDE LINKER AND SIDE-CHAIN HYDROPHILIC FRAGMENT COMBINED GLYCOSITE-SPECIFIC ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-02-09 | — | — | WO | disclosed |