Sugi Predict

Sugi Predict / Compounds / SCHEMBL908481

SCHEMBL908481

SCHEMBL908481

Cc1cn(CC(=O)O)nn1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.43
▸ SRC P12931 3/20 0.41
▸ MAPK14 Q16539 1/20 0.39
▸ HTT P42858 2/20 0.39
▸ ALDH1A1 P00352 4/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ GAA P10253 2/20 0.38
▸ EPHX2 P34913 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ NR1H4 Q96RI1 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ KMT2A Q03164 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1375015 0.98 LMNA (0.42) LMNASRCMAPK14HTTALDH1A1
SCHEMBL11910527 0.84 SRC (0.41) LMNASRCALDH1A1MAPTGLA
SCHEMBL12984349 0.82 SMYD3 (0.44) LMNASRCHTTALDH1A1GLA
SCHEMBL13167820 0.81 SRC (0.39) LMNASRCALDH1A1POLBGLA
SCHEMBL21984860 0.79 NTRK1 (0.41) SRCPOLBGAAGLAKMT2A
SCHEMBL908777 0.78 MAPK1 (0.50) LMNASRCMAPK14ALDH1A1KDM4E
SCHEMBL22894464 0.78 SRC (0.37) LMNASRCMAPK14ALDH1A1POLB
SCHEMBL2628186 0.77 CYP4F2 (0.40) SRCHTTPOLBGAAKMT2A
SCHEMBL25015657 0.77 GLA (0.42) SRCALDH1A1POLBGAAGLA
SCHEMBL4134269 0.76 DPP4 (0.43) LMNASRCMAPK14HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767336-B2 Organometallic cluster photoresists for EUV lithography TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2023-09-26 — — US disclosed
CN-116568676-A IL-17A modulators 赛诺菲 2023-08-08 — — CN disclosed
CN-116547275-A IL-17A modulators 赛诺菲 2023-08-04 — — CN disclosed
WO-2023049796-A1 RelA/RSH INHIBITORS FOR THE TREATMENT OR PREVENTION OF MEDICAL BIOFILMS DREXEL UNIVERSITY (US) 2023-03-30 — — WO disclosed
EP-3592741-B1 NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS PFIZER (US) 2023-02-15 — — EP disclosed
US-11579531-B2 Organometallic cluster photoresists for EUV lithography TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2023-02-14 — — US disclosed
CN-111051304-B Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors 辉瑞大药厂 2022-12-27 — — CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 — — US disclosed
US-20220125958-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY PURDUE RESEARCH FOUNDATION 2022-04-28 — — US disclosed
US-11312713-B2 Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors PFIZER INC. (US) 2022-04-26 — — US disclosed
WO-2009124166-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK & CO., INC. (US) 2009-10-08 — — WO disclosed
WO-2009124166-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK & CO., INC. (US) 2009-10-08 — — WO disclosed
US-20090253705-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK SHARP & DOHME LLC 2009-10-08 — — US disclosed
US-20090253705-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK SHARP & DOHME LLC 2009-10-08 — — US disclosed
US-20090253705-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK SHARP & DOHME LLC 2009-10-08 — — US disclosed
WO-2009124167-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK & CO., INC. (US) 2009-10-08 — — WO disclosed
WO-2009124167-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS MERCK & CO., INC. (US) 2009-10-08 — — WO disclosed
EP-2084151-A1 SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HAEMATOLOGICAL DISEASES Bayer HealthCare AG (DE) 2009-08-05 — — EP disclosed
US-20090162424-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING MULTIFUNCTIONAL POLYMERIZED LIPOSOMES UNIVERSITY OF HOUSTON 2009-06-25 — — US disclosed
WO-2008067871-A1 SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HAEMATOLOGICAL DISEASES BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-06-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11579531-B2 Organometallic cluster photoresists for EUV lithography ETV6, CDV3, RUVBL2 LMNA 3794/4885SRC 1233/4885MAPK14 3935/4885
US-20090253705-A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS ADRB3, ADRB1, ADRB2 LMNA 1232/4885SRC 3841/4885MAPK14 4753/4885
US-11312713-B2 Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors LRRK2, PARK7, BRCA1 LMNA 2226/4885SRC 1040/4885MAPK14 1017/4885
US-11767336-B2 Organometallic cluster photoresists for EUV lithography ETV6, CDV3, RUVBL2 LMNA 3794/4885SRC 1233/4885MAPK14 3935/4885
US-20220125958-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY FOLH1, FOLR2, FOLR1 LMNA 1873/4885SRC 3751/4885MAPK14 3672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.