Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 7/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 4/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015750 | 0.94 | CCR2 (0.36) | RHEBMCL1CCR2FDPSCCR9 | |
| SCHEMBL25016848 | 0.91 | F10 (0.40) | KMT2A | |
| SCHEMBL25015942 | 0.89 | RHEB (0.33) | RHEBMCL1CCR2FDPSCCR9 | |
| SCHEMBL25016881 | 0.89 | RHEB (0.36) | RHEBMCL1CCR2FDPSCCR9 | |
| SCHEMBL25015936 | 0.88 | KMT2A (0.33) | KMT2A | |
| SCHEMBL25016863 | 0.86 | F10 (0.41) | — | |
| SCHEMBL25017508 | 0.86 | F10 (0.41) | RHEBMCL1CCR2FDPS | |
| SCHEMBL25015779 | 0.85 | F10 (0.44) | KMT2A | |
| SCHEMBL25017211 | 0.82 | RHEB (0.40) | RHEBMCL1CCR2FDPSCCR9 | |
| SCHEMBL21822217 | 0.82 | F10 (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | RHEB 4691/4885MCL1 3593/4885CCR2 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.