Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25018132 | 0.97 | SPHK2 (0.30) | SPHK2SPHK1 | |
| SCHEMBL21026098 | 0.77 | OPRM1 (0.33) | SPHK2SPHK1 | |
| SCHEMBL25960290 | 0.77 | OPRM1 (0.33) | SPHK2SPHK1 | |
| SCHEMBL23545040 | 0.77 | OPRM1 (0.33) | SPHK2SPHK1 | |
| SCHEMBL18661777 | 0.76 | DNM1 (0.33) | SPHK2SPHK1 | |
| SCHEMBL20653484 | 0.76 | OPRM1 (0.36) | SPHK2SPHK1 | |
| SCHEMBL24092050 | 0.76 | OPRM1 (0.36) | SPHK2SPHK1 | |
| SCHEMBL25017811 | 0.74 | MAPT (0.33) | MAPT | |
| SCHEMBL24092061 | 0.74 | OPRM1 (0.35) | SPHK2SPHK1 | |
| SCHEMBL20244060 | 0.73 | MAPT (0.37) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143804-A1 | FLUOROALKYL-OXADIAZOLES AND USES THEREOF | TENAYA THERAPEUTICS, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11578066-B1 | Fluoroalkyl-oxadiazoles and uses thereof | TENAYA THERAPEUTICS, INC. (US) | 2023-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578066-B1 | Fluoroalkyl-oxadiazoles and uses thereof | HDAC6, HDAC1, HDAC3 | SPHK2 380/4885SPHK1 653/4885MAPT 581/4885 |
| US-20230143804-A1 | FLUOROALKYL-OXADIAZOLES AND USES THEREOF | HDAC6, HDAC1, HDAC3 | SPHK2 614/4885SPHK1 957/4885MAPT 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.