Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 4/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21132890 | 1.00 | IDO1 (0.47) | IDO1TDO2P2RX7PDE2ACCR1 | |
| SCHEMBL30991133 | 0.87 | IDO1 (0.44) | IDO1TDO2P2RX7PDE2ACCR1 | |
| SCHEMBL21132974 | 0.87 | P2RX7 (0.39) | IDO1TDO2P2RX7PDE2ASOS1 | |
| SCHEMBL25020679 | 0.87 | P2RX7 (0.39) | IDO1TDO2P2RX7PDE2ASOS1 | |
| SCHEMBL12009462 | 0.84 | P2RX7 (0.50) | IDO1TDO2P2RX7PDE2ACCR1 | |
| SCHEMBL16649602 | 0.82 | IDO1 (0.47) | IDO1TDO2P2RX7PDE2ACCR1 | |
| SCHEMBL16649567 | 0.82 | IDO1 (0.47) | IDO1TDO2P2RX7PDE2ACCR1 | |
| SCHEMBL13168657 | 0.82 | ACP3 (0.47) | P2RX7PDE2AACP3 | |
| SCHEMBL29907993 | 0.82 | ACP3 (0.47) | P2RX7PDE2AACP3 | |
| SCHEMBL29580255 | 0.82 | ACP3 (0.47) | P2RX7PDE2AACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219493-A1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |
| EP-3728254-B1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-02-15 | — | — | EP | disclosed |