SCHEMBL2502004

SCHEMBL2502004

C[SiH](C)C=CCCN1CCCC1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
HRH3 Q9Y5N1 2/20 0.36
SIGMAR1 Q99720 2/20 0.34
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2501227 0.98 HRH3 (0.39) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL2509150 0.86 HRH3 (0.46) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL2506359 0.79 CARM1 (0.34) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL2506874 0.77 CARM1 (0.35) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL3381213 0.76 LTA4H (0.33) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL2502434 0.75 HRH3 (0.38) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL16676782 0.75 CARM1 (0.41) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL10379098 0.74
SCHEMBL14030075 0.73 CARM1 (0.39) CARM1PRMT6PRMT8HRH3SIGMAR1
SCHEMBL7830818 0.72 HRH3 (0.48) CARM1PRMT6PRMT8HRH3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304488-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-06 US disclosed
US-20110245408-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed