SCHEMBL2501227

SCHEMBL2501227

C[SiH](C)C=CCCN1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.39
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
SIGMAR1 Q99720 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ABCB1 P08183 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502004 0.98 CARM1 (0.37) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL2509150 0.88 HRH3 (0.46) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL3381213 0.78 LTA4H (0.33) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL2502434 0.78 HRH3 (0.38) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL2506359 0.78 CARM1 (0.34) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL2506874 0.75 CARM1 (0.35) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL7830818 0.75 HRH3 (0.48) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL16676782 0.73 CARM1 (0.41) HRH3CARM1PRMT6PRMT8SIGMAR1
SCHEMBL10379098 0.72
SCHEMBL15710532 0.72 L3MBTL1 (0.52) HRH3ALDH1A1CYP1A2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304488-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-06 US disclosed
US-20110245408-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed