Protizinic Acid

Protizinic Acid

SCHEMBL25022

COc1ccc2c(c1)Sc1ccc(C(C)C(=O)O)cc1N2C

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 5/20 0.54
AKR1C2 P52895 5/20 0.54
PTGS2 P35354 4/20 0.54
PTGS1 P23219 2/20 0.54
TSHR P16473 2/20 0.54
CDC42 P60953 1/20 0.54
RAC1 P63000 1/20 0.54
CYP1A2 P05177 1/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SNCA P37840 5/20 0.52
APP P05067 1/20 0.47
CYP2C19 P33261 1/20 0.47
TP53 P04637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protizinic Acid SCHEMBL29359535 1.00 AKR1C3 (0.54) AKR1C3AKR1C2PTGS2PTGS1TSHR
Protizinic Acid SCHEMBL18309842 1.00 AKR1C3 (0.54) AKR1C3AKR1C2PTGS2PTGS1TSHR
Protizinic Acid SCHEMBL8208239 0.89 AKR1C3 (0.44) AKR1C3AKR1C2PTGS2PTGS1TSHR
SCHEMBL2739325 0.85 SNCA (0.59) PTGS1CYP1A2SNCATP53KDM4E
SCHEMBL10618628 0.82 NOX1 (0.58) AKR1C3AKR1C2PTGS2PTGS1TSHR
SCHEMBL11255517 0.82 SNCA (0.53) PTGS1CYP1A2SNCATP53KDM4E
Protizinic Acid SCHEMBL2072946 0.80 PTGS1 (0.63) AKR1C3AKR1C2PTGS2PTGS1TSHR
SCHEMBL7389154 0.77 SNCA (0.81) SNCATP53KDM4EMAPK1MAPT
SCHEMBL10941736 0.76 TP53 (0.39) PTGS2TSHRSNCATP53KDM4E
SCHEMBL2760350 0.75 SNCA (0.64) SNCATP53KDM4EMAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3575 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4470565-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT OnQuality Pharmaceuticals China Ltd. (CN) 2024-12-04 EP claimed
US-RE50218-E1 Non-steroidal anti-inflammatory ophthalmic compositions SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-11-26 US claimed
CN-118742325-A Methods for preventing or treating diseases or conditions associated with antineoplastic agents 上海岸阔医药科技有限公司 2024-10-01 CN claimed
WO-2024105529-A1 CHEMICAL DISBUDDING OF LIVESTOCK MASSEY UNIVERSITY (NZ) 2024-05-23 WO claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP claimed
WO-2023142996-A1 METHOD FOR PREVENTING OR TREATING DISEASE OR DISORDER ASSOCIATED WITH ANTINEOPLASTIC AGENT 上海岸阔医药科技有限公司 2023-08-03 WO claimed
WO-2023075715-A1 A PHARMACEUTICAL FORMULATION INCLUDING LEUKOTRIENE RECEPTOR ANTAGONISTS AND/OR LEUKOTRIENE SYNTHESIS INHIBITORS COMBINED WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS) VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI (TR) 2023-05-04 WO claimed
EP-4034087-A1 LIPID VESICLE COMPOSITIONS WITH PENETRATION ENHANCING AGENTS DDS Research Inc. (CA) 2022-08-03 EP claimed
US-20220218611-A1 LIPID VESICLE COMPOSITIONS WITH PENETRATION ENHANCING AGENTS DDS RESEARCH INC. (CA) 2022-07-14 US claimed
EP-0205215-B1 PROCESS FOR THE PREPARATION OF 2-ARYLPROPIONIC ACIDS GIST-BROCADES N.V. (NL) 1990-08-08 EP claimed
EP-0374602-A1 Lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1990-06-27 EP claimed
US-4886750-A STEREOSELECTIVE HYDROLYSIS USING MICROORGANISMS GIST-BROCADES N.V. (NL) 1989-12-12 US claimed
EP-0274146-A1 Process for the preparation of 2-arylpropionic acids GIST-BROCADES N.V. (NL) 1988-07-13 EP claimed
CN-87100031-A The preparation method of 2-arylpropionic acid 1987-09-09 CN claimed
EP-0233656-A1 Microbial esterase and process for the preparation of 2-arylpropionic acids GIST-BROCADES N.V. (NL) 1987-08-26 EP claimed
CN-86103879-A Provide the method for 2-arylpropionic acid for oneself 1987-04-08 CN claimed
EP-0205215-A2 Process for the preparation of 2-arylpropionic acids GIST-BROCADES N.V. (NL) 1986-12-17 EP claimed
EP-0072462-B1 PHARMACEUTICAL PREPARATIONS Toko Yakuhin Industry Co., Ltd. (JP) 1986-10-29 EP claimed
EP-0072462-A2 Pharmaceutical preparations Toko Yakuhin Industry Co., Ltd. (JP) 1983-02-23 EP claimed