Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739325 | 0.86 | SNCA (0.59) | SNCALMNAMAPK1TP53KDM4E | |
| Protizinic Acid SCHEMBL29359535 | 0.82 | AKR1C3 (0.54) | SNCALMNAMAPK1TP53KDM4E | |
| Protizinic Acid SCHEMBL18309842 | 0.82 | AKR1C3 (0.54) | SNCALMNAMAPK1TP53KDM4E | |
| Protizinic Acid SCHEMBL25022 | 0.82 | AKR1C3 (0.54) | SNCALMNAMAPK1TP53KDM4E | |
| SCHEMBL7389154 | 0.78 | SNCA (0.81) | SNCALMNAMAPK1TP53KDM4E | |
| SCHEMBL2760350 | 0.76 | SNCA (0.64) | SNCALMNAMAPK1TP53KDM4E | |
| SCHEMBL7123151 | 0.74 | SNCA (0.69) | SNCALMNAMAPK1TP53KDM4E | |
| Protizinic Acid SCHEMBL8208239 | 0.73 | AKR1C3 (0.44) | SNCALMNAMAPK1TP53KDM4E | |
| SCHEMBL2706164 | 0.72 | NOX1 (0.46) | SNCALMNAMAPK1PKMMEN1 | |
| SCHEMBL31297952 | 0.71 | MAOA (0.63) | SNCALMNAMAPK1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |