SCHEMBL578972

SCHEMBL578972

CCCOCCCOCCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
CYP3A4 P08684 1/20 0.42
HSD17B10 Q99714 1/20 0.41
USP2 O75604 1/20 0.37
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CES2 O00748 1/20 0.35
HPGD P15428 1/20 0.35
SPHK2 Q9NRA0 1/20 0.34
LMNA P02545 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17580775 0.96 HTT (0.48) TSHRHTTMEN1THRBKMT2A
SCHEMBL4331765 0.93 TSHR (0.60) TSHRHTTMEN1THRBKMT2A
SCHEMBL2323645 0.92 TSHR (0.50) TSHRHTTMEN1THRBKMT2A
SCHEMBL2551087 0.92 TSHR (0.50) TSHRHTTMEN1THRBKMT2A
SCHEMBL874663 0.90 TSHR (0.43) TSHRHTTMEN1THRBKMT2A
SCHEMBL25634275 0.90 TSHR (0.57) TSHRHTTMEN1THRBKMT2A
SCHEMBL627684 0.90 TSHR (0.43) TSHRHTTMEN1THRBKMT2A
Ammonia Solution, Strong SCHEMBL16735225 0.89 HTT (0.48) TSHRHTTMEN1THRBKMT2A
SCHEMBL6900939 0.89 HTT (0.55) TSHRHTTMEN1THRBKMT2A
SCHEMBL6897104 0.89 HTT (0.55) TSHRHTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240309160-A1 PROCESS FOR PRODUCING ISOCYANATE-BASED FOAM CONSTRUCTION BOARDS AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2024-09-19 US claimed
CN-112574339-B Multi-element external electron donor composition for olefin polymerization, olefin polymerization catalyst comprising same, and olefin polymerization method 中国石油天然气股份有限公司 2022-07-05 CN claimed
CN-113439098-A Recyclable and reprocessable epoxy resins 阿迪塔亚博拉化学品(泰国)有限公司 2021-09-24 CN claimed
CN-112574339-A Multi-element external electron donor composition for olefin polymerization, olefin polymerization catalyst comprising same, and olefin polymerization method 中国石油天然气股份有限公司 2021-03-30 CN claimed
CN-105189661-A Filler with surface coating made of water-soluble polyamide EMS PATENT AG 2015-12-23 CN claimed
US-7790629-B2 Atomic layer deposition of strontium oxide via N-propyltetramethyl cyclopentadiendyl precursor THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2010-09-07 US claimed
US-20080242111-A1 Atomic layer deposition of strontium oxide via n-propyltetramethyl cyclopentadiendyl precursor BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE 2008-10-02 US claimed
WO-2008100616-A2 ATOMIC LAYER DEPOSITION OF STRONTIUM OXIDE VIA N-PROPYLTETRAMETHYL CYCLOPENTADIENYL PRECURSOR THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-08-21 WO claimed
EP-1313747-B1 METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2005-04-20 EP claimed
US-6784305-B2 DERIVATIVES OF ZIRCONOCENE DICHLORIDE IN WHICH THE TWO SUBSTITUTED INDENYL GROUPS ARE JOINED TO ONE ANOTHER VIA A BRIDGE CAN, OWING TO THEIR CONFORMATIONAL RIGIDITY, BE USED AS CATALYSTS FOR THE STEREOSPECIFIC POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-08-31 US claimed
US-20030199703-A1 Method for producing alkyl-bridged ligand systems and transition metal compounds EQUISTAR CHEMICALS, LP 2003-10-23 US claimed
EP-1313747-A1 METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS Basell Polypropylen GmbH (DE) 2003-05-28 EP claimed
WO-2002018397-A1 METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS BASELL POLYPROPYLEN GMBH (DE) 2002-03-07 WO claimed
EP-0719800-A1 Catalysts for the (co)polymerization of ethylene Montell Technology Company bv (NL) 1996-07-03 EP claimed
US-12624318-B2 Cleaning agent composition and cleaning method NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
US-20260015441-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2026-01-15 US disclosed
US-20250376645-A1 METHOD FOR PRODUCING PROCESSED SEMICONDUCTOR SUBSTRATE NISSAN CHEMICAL CORPORATION (JP) 2025-12-11 US disclosed
EP-0501167-B1 Liquid dye preparations BASF AG (DE) 1995-07-05 EP disclosed
US-5205838-A LIQUID DYE PREPARATIONS: BIS PHENYL-AZO-RESORCINOL IN SOLVENT FOR COLORED RIBBON OR BALL PEN INK BASF AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
EP-0501167-A1 Liquid dye preparations BASF Aktiengesellschaft (DE) 1992-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199703-A1 Method for producing alkyl-bridged ligand systems and transition metal compounds ABL1, ICMT, ORAI2 TSHR 1526/4885HTT 1958/4885MEN1 1538/4885
US-20260015441-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS P4HA1, TCP1, PPT1 TSHR 2212/4885HTT 1019/4885MEN1 978/4885
US-12624318-B2 Cleaning agent composition and cleaning method DNMT1, TLN1, TET2 TSHR 1850/4885HTT 1126/4885MEN1 1426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.