Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XPO1 | O14980 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091171 | 0.84 | GAA (0.52) | HCAR3POLBGAAEPHX2RAB9A | |
| SCHEMBL13312903 | 0.83 | HCAR3 (0.49) | HCAR3POLBGAARAB9ANPC1 | |
| SCHEMBL6362419 | 0.78 | GAA (0.52) | HCAR3POLBGAAEPHX2RAB9A | |
| SCHEMBL25651333 | 0.78 | POLB (0.41) | HCAR3POLBGAAEPHX2RAB9A | |
| SCHEMBL20988194 | 0.76 | GAA (0.53) | POLBGAAEPHX2RAB9ANPC1 | |
| SCHEMBL19122046 | 0.76 | HCAR3 (0.61) | HCAR3GAARAB9AALDH1A1HCAR2 | |
| SCHEMBL4219951 | 0.76 | RAB9A (0.56) | HCAR3POLBGAARAB9ANPC1 | |
| SCHEMBL21374820 | 0.75 | GAA (0.41) | POLBGAAEPHX2RAB9ANPC1 | |
| SCHEMBL2793492 | 0.75 | HCAR3 (0.59) | HCAR3ALDH1A1PTGS1HCAR2TP53 | |
| SCHEMBL4970731 | 0.75 | HCAR3 (0.59) | HCAR3ALDH1A1PTGS1HCAR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018781-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2023-02-16 | — | — | WO | disclosed |