SCHEMBL25025465

SCHEMBL25025465

CCCCCCCC(=O)NCCOCCOCOC1C(O)[C@@H](CO)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ADORA1 P30542 8/20 0.49
▸ ADORA3 P0DMS8 2/20 0.48
▸ ADORA2A P29274 2/20 0.48
▸ ADORA2B P29275 2/20 0.48
▸ SLC29A1 Q99808 1/20 0.47
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ P2RY12 Q9H244 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25025464 1.00 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL25025575 1.00 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL26238484 1.00 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL25025462 1.00 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL26240496 1.00 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL25025558 0.99 ADORA1 (0.49) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL4455502 0.87 SLC29A1 (0.55) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL7245383 0.87 SLC29A1 (0.55) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL19509820 0.87 ADORA1 (0.50) ADORA1ADORA3ADORA2AADORA2BSLC29A1
SCHEMBL21652362 0.87 ADORA1 (0.50) ADORA1ADORA3ADORA2AADORA2BSLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230277675-A1 SYSTEMIC DELIVERY OF OLIGONUCLEOTIDES NOVO NORDISK A/S (DK) 2023-09-07 — — US disclosed
WO-2022031433-A9 SYSTEMIC DELIVERY OF OLIGONUCLEOTIDES DICERNA PHARMACEUTICALS, INC. (US) 2023-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277675-A1 SYSTEMIC DELIVERY OF OLIGONUCLEOTIDES DCLRE1B, RNMT, CD2BP2 ADORA1 421/4885ADORA3 139/4885ADORA2A 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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