Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234302 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL25025538 | 1.00 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL16962406 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL25211397 | 0.76 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT | |
| SCHEMBL23858280 | 0.75 | HTR2C (0.59) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2A | |
| SCHEMBL25090547 | 0.74 | HTR2C (0.58) | HTR2AKDM1AHTR2CHTR2BDRD2 | |
| SCHEMBL25090261 | 0.74 | HTR2C (0.58) | HTR2AKDM1AHTR2CHTR2BDRD2 | |
| SCHEMBL25090545 | 0.74 | HTR2C (0.58) | HTR2AKDM1AHTR2CHTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL23858241 | 0.73 | HTR2C (0.60) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2A | |
| SCHEMBL21009648 | 0.73 | ALDH1A1 (0.48) | CHRNB2CHRNA4CHRNB4CHRNA3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023018781-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2023-02-16 | — | — | WO | disclosed |