Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25025898 | 0.92 | NR4A2 (0.48) | NR4A2MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL25565262 | 0.85 | MTNR1A (0.53) | NR4A2MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL25025846 | 0.85 | MTNR1A (0.42) | NR4A2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL25025782 | 0.82 | NR4A2 (0.49) | NR4A2MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL6100002 | 0.81 | NR4A2 (0.61) | NR4A2MTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL25554541 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BHTR1A | |
| SCHEMBL25554592 | 0.79 | STING1 (0.36) | NR4A2MTNR1AMTNR1BMAPTHTR4 | |
| SCHEMBL25025532 | 0.79 | S1PR1 (0.45) | HTR1A | |
| SCHEMBL25554596 | 0.79 | STING1 (0.36) | NR4A2MTNR1AMTNR1BMAPTHTR4 | |
| SCHEMBL25025916 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018781-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2023-02-16 | — | — | WO | disclosed |