Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25026083 | 0.85 | NR4A2 (0.53) | MTNR1AMTNR1BNR4A2LMNAKDM4E | |
| SCHEMBL25025898 | 0.80 | NR4A2 (0.48) | MTNR1AMTNR1BNR4A2LMNAKDM4E | |
| SCHEMBL25212609 | 0.77 | TRPV1 (0.39) | MTNR1AMTNR1BTRPV1FAAH | |
| SCHEMBL25025699 | 0.77 | TRPV1 (0.39) | MTNR1AMTNR1BTRPV1FAAH | |
| SCHEMBL6100002 | 0.77 | NR4A2 (0.61) | MTNR1AMTNR1BNR4A2LMNAKDM4E | |
| SCHEMBL28680395 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BNR4A2LMNAKDM4E | |
| SCHEMBL25557628 | 0.75 | TRPV1 (0.34) | MTNR1AMTNR1BALDH1A1TRPV1FAAH | |
| SCHEMBL25564619 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BNR4A2LMNAKDM4E | |
| SCHEMBL25025846 | 0.73 | MTNR1A (0.42) | MTNR1AMTNR1BNR4A2KDM4EALDH1A1 | |
| SCHEMBL25559500 | 0.72 | NR4A2 (0.54) | MTNR1AMTNR1BNR4A2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167057-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167057-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | MTNR1A 2205/4885MTNR1B 2787/4885NR4A2 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.