Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26463849 | 0.80 | CYP11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL23571237 | 0.79 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL23571253 | 0.79 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL20844090 | 0.76 | TSHR (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL13259739 | 0.72 | ESR1 (0.30) | — | |
| SCHEMBL30556664 | 0.71 | PDE1A (0.35) | — | |
| SCHEMBL21361275 | 0.71 | GPR84 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL18971809 | 0.71 | ESR1 (0.32) | — | |
| SCHEMBL2737342 | 0.70 | P2RX3 (0.33) | — | |
| SCHEMBL25027485 | 0.69 | CYP11B1 (0.31) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| WO-2023017263-A1 | POTASSIUM CHANNEL MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303514-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | CYP11B1 1142/4885CYP11B2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.