SCHEMBL2502775

SCHEMBL2502775

C=C(C)C(=O)OCCOC(CC)[Si](OC)(OC)OC

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7996700 0.85 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8749911 0.84 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10885741 0.83 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8462882 0.81 THRB (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7866736 0.81 THRB (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8864115 0.81 TSHR (0.33) THRBTSHRALDH1A1
SCHEMBL10661650 0.80 THRB (0.42) THRBTSHRALDH1A1
SCHEMBL10658990 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10887313 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10889693 0.79 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110244113-A1 METHOD OF TOOTH SURFACE TREATMENT GC CORPORATION (JP) 2011-10-06 US disclosed
EP-1532958-B1 Dental surface coating material G C DENTAL IND CORP (JP) 2009-03-04 EP disclosed
US-20050113480-A1 Photopolymerization type dental surface coating material GC CORPORATION (JP) 2005-05-26 US disclosed
EP-1532958-A1 Photopolymerization type dental surface coating material GC Corporation (JP) 2005-05-25 EP disclosed
US-6300389-B1 USED AS A DENTAL FILLING RESTORATION MATERIAL, A REBUILDING MATERIAL OF ABUTMENT TOOTH, A SEALING MATERIAL PIT AND FISSURE, DENTAL PROSTHESES SUCH AS AN INLAY, A CROWN, AND A BRIDGE, A RESIN CEMENT, AND A DENTURE MATERIAL GC CORPORATION (JP) 2001-10-09 US disclosed
US-5962550-A BLEND OF GLASS POWDER AND ACRYLIC POLYMER GC CORPORATION (JP) 1999-10-05 US disclosed
US-5773489-A TITANIUM, ZIRCONIUM, YTTRIUM, LANTHANUM, TANTALUM, ALUMINUM OXIDES LINKED TO ORGANIC REACTIVE COMPOUND GC CORPORATION (JP) 1998-06-30 US disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed