Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661650 | 0.95 | THRB (0.42) | THRBTSHRALDH1A1 | |
| SCHEMBL10887313 | 0.88 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10889693 | 0.88 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL8462882 | 0.85 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2502775 | 0.85 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10888396 | 0.85 | THRB (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL10890334 | 0.85 | THRB (0.43) | THRBTSHRALDH1A1 | |
| SCHEMBL10888425 | 0.82 | THRB (0.41) | THRBTSHRALDH1A1 | |
| SCHEMBL10658990 | 0.82 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7866736 | 0.82 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60131518-A | — | — | None | — | — | JP | disclosed |
| US-6286955-B1 | CONTACT LENSES IN WHICH ALKOXYALKYL (METH)ACRYLATE (CO)POLYMER LAYER IS FORMED ON THE SURFACE OF THE LENS; FREE FROM ADHESION AND EASILY CLEANED OF LIPID AND PROTEINS IN TEARS | Sakai, Tetsuya (JP) | 2001-09-11 | — | — | US | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |
| JP-S60131518-A | CONTACT LENS MATERIAL | NIPPON CONTACT LENS SEIZO KK | 1985-07-13 | — | — | JP | disclosed |