Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895148 | 1.00 | KDM4E (0.48) | KDM4ERAB9ANPC1POLBROCK2 | |
| SCHEMBL29226888 | 0.93 | RAB9A (0.49) | KDM4ERAB9ANPC1POLBROCK2 | |
| SCHEMBL29979571 | 0.89 | MAPT (0.41) | KDM4ERAB9ANPC1POLBFAAH | |
| SCHEMBL23769056 | 0.89 | MAPT (0.41) | KDM4ERAB9ANPC1POLBFAAH | |
| SCHEMBL30248501 | 0.87 | KDM4E (0.47) | KDM4ERAB9ANPC1POLBROCK2 | |
| SCHEMBL25028533 | 0.87 | KDM4E (0.47) | KDM4ERAB9ANPC1POLBROCK2 | |
| SCHEMBL23768832 | 0.83 | TRPV1 (0.43) | KDM4ERAB9ANPC1POLBFAAH | |
| SCHEMBL29978948 | 0.83 | TRPV1 (0.43) | KDM4ERAB9ANPC1POLBFAAH | |
| SCHEMBL30895162 | 0.82 | ROCK2 (0.44) | KDM4ERAB9ANPC1POLBROCK2 | |
| SCHEMBL25028041 | 0.82 | ROCK2 (0.44) | KDM4ERAB9ANPC1POLBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |