Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030230 | 1.00 | FPR3 (0.36) | FPR3FPR2SMN1; SMN2TP53BCHE | |
| SCHEMBL26059633 | 1.00 | FPR3 (0.36) | FPR3FPR2SMN1; SMN2TP53BCHE | |
| SCHEMBL25029689 | 0.89 | BCHE (0.34) | SMN1; SMN2BCHEPAOXSIGMAR1TSHR | |
| SCHEMBL25029686 | 0.88 | KCNH2 (0.43) | BCHE | |
| SCHEMBL26202904 | 0.84 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL25029687 | 0.82 | NPC1 (0.40) | TSHRKDM4EALDH1A1 | |
| SCHEMBL25028805 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2OPRL1KDM4EALDH1A1 | |
| SCHEMBL25631007 | 0.77 | OPRL1 (0.38) | TP53SIGMAR1OPRL1KDM4EALDH1A1 | |
| SCHEMBL26059631 | 0.76 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL25631008 | 0.76 | HRH3 (0.40) | TP53TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017484-A1 | CYTOTOXICITY TARGETING CHIMERAS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |