Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612892 | 0.88 | TSHR (0.41) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL2537711 | 0.88 | TSHR (0.41) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL6613066 | 0.88 | TSHR (0.41) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL16926969 | 0.88 | TSHR (0.41) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL28914857 | 0.85 | TSHR (0.39) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL850797 | 0.85 | — | — | |
| SCHEMBL7454479 | 0.85 | TSHR (0.56) | TSHRCYP3A4ALDH1A1TDP1MAPT | |
| SCHEMBL11225741 | 0.85 | — | — | |
| SCHEMBL1460543 | 0.85 | TSHR (0.43) | TSHRCYP3A4LTB4RALDH1A1TDP1 | |
| SCHEMBL14351852 | 0.85 | TSHR (0.56) | TSHRCYP3A4ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017483-A1 | CYTOTOXICITY TARGETING CHIMERAS FOR CCR2-EXPRESSING CELLS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |